Differential expression of viral PAMP receptors mRNA in peripheral blood of patients with chronic hepatitis C infection

@article{Atencia2007DifferentialEO,
  title={Differential expression of viral PAMP receptors mRNA in peripheral blood of patients with chronic hepatitis C infection},
  author={Rafael Atencia and Francisco Javier Bustamante and Andr{\'e}s Valdivieso and Arantza Arrieta and Marta Ri{\~n}{\'o}n and Alvaro Prada and Natalia Maruri},
  journal={BMC Infectious Diseases},
  year={2007},
  volume={7},
  pages={136 - 136}
}
BACKGROUND Pathogen-associated molecular patterns (PAMP) receptors play a key role in the early host response to viruses. In this work, we determined mRNA levels of two members of the Toll-like Receptors family, (TLR3 and TLR7) and the helicase RIG-I, all of three recognizing viral RNA products, in peripheral blood of healthy donors and hepatitis C virus (HCV) patients, to observe if their transcripts are altered in this disease. METHODS IFN-alpha, TLR3, TLR7 and RIG-I levels in peripheral… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Hepatitis C virus' initial encounters: mechanisms of innate immunity.

Frontiers in bioscience • 2012
View 18 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF.

Proceedings of the National Academy of Sciences of the United States of America • 2005
View 4 Excerpts
Highly Influenced

Toll-like receptor 3 promotes cross-priming to virus-infected cells

O Schultz, SS Diebold, +8 authors C Sousa
Nature • 2005
View 5 Excerpts
Highly Influenced

Toll-like receptor signalling

Nature Reviews Immunology • 2004
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…