Differential expression of three estrogen receptor subtype mRNAs in gonads and liver from embryos to adults of the medaka, Oryzias latipes.

@article{Chakraborty2011DifferentialEO,
  title={Differential expression of three estrogen receptor subtype mRNAs in gonads and liver from embryos to adults of the medaka, Oryzias latipes.},
  author={Tapas Chakraborty and Yasushi Shibata and Lin-yan Zhou and Yoshinao Katsu and Taisen Iguchi and Yoshitaka Nagahama},
  journal={Molecular and cellular endocrinology},
  year={2011},
  volume={333 1},
  pages={47-54}
}
In fish, estradiol-17β (E2) regulates various reproductive processes by acting through estrogen receptors (ERs). Here, we cloned three ER subtypes from medaka and examined their developmental expression in the gonads and liver of genetically females and males from embryos to adults. During embryogenesis, marked increases in the expression of ERβ2, but not either ERα or ERβ1, were found in genetically female embryos during sex differentiation. E2 treatment induced marked up-regulation of ERβ2… CONTINUE READING
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