Differential expression of the tick protective antigen subolesin in anaplasma marginale- and A. phagocytophilum-infected host cells.

@article{Fuente2008DifferentialEO,
  title={Differential expression of the tick protective antigen subolesin in anaplasma marginale- and A. phagocytophilum-infected host cells.},
  author={Jos{\'e} de la Fuente and Edmour F. Blouin and Ra{\'u}l Manzano-Rom{\'a}n and Victoria Naranjo and Consuelo Almaz{\'a}n and Jos{\'e} Manuel P{\'e}rez de la Lastra and Zorica Zivkovic and Robert F. Massung and Frans Jongejan and Katherine M. Kocan},
  journal={Annals of the New York Academy of Sciences},
  year={2008},
  volume={1149},
  pages={27-35}
}
Subolesin was recently shown in vaccine and RNA interference (RNAi) studies to protect against tick infestations and to affect tick feeding, reproduction, and development as well as infection of host cells by Anaplasma marginale and A. phagocytophilum. Recent experiments provided evidence that infection of both tick and vertebrate host cells with these two pathogens modified gene expression. We therefore hypothesized that infection of host cells with A. marginale and A. phagocytophilum affects… CONTINUE READING

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