Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes.

@article{Chen2006DifferentialEO,
  title={Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes.},
  author={Jing Chen and Scott W. Boyle and Min Zhao and Wei Su and Keiko F Takahashi and Linda Davis and Mark Decaestecker and Takamune Takahashi and Matthew D. Breyer and Chuan-ming Hao},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2006},
  volume={17 5},
  pages={1283-91}
}
Nestin, an intermediate filament protein, is widely used as stem cell marker. Nestin has been shown to interact with other cytoskeleton proteins, suggesting a role in regulating cellular cytoskeletal structure. These studies examined renal nestin localization and developmental expression in mice. In developing kidney, anti-nestin antibody revealed strong immunoreactivity in vascular cleft of the S-shaped body and vascular tuft of capillary loop-stage glomerulus. The nestin-positive structures… CONTINUE READING