Differential expression of the TRAIL/TRAIL-receptor system in patients with inflammatory bowel disease.

@article{Brost2010DifferentialEO,
  title={Differential expression of the TRAIL/TRAIL-receptor system in patients with inflammatory bowel disease.},
  author={Sylvia Brost and Ronald Koschny and Jaromir Sykora and Wolfgang Stremmel and Felix Lasitschka and Henning Walczak and Tom M. Ganten},
  journal={Pathology, research and practice},
  year={2010},
  volume={206 1},
  pages={43-50}
}
TNF-related apoptosis inducing-ligand (TRAIL) is a potent inducer of apoptosis and plays an important role in immune regulation. To explore the role of TRAIL in inflammatory bowel disease (IBD), we examined the expression of the TRAIL/TRAIL-receptor system in colonic resections from patients with ulcerative colitis and Crohn's disease in comparison to normal colon and appendicitis. TRAIL and TRAIL-receptor (TRAIL-R) expression was assessed in resections of normal colon, colon of IBD patients… CONTINUE READING

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