Differential expression of prostaglandin D2 synthase (PTGDS) in patients with attention deficit-hyperactivity disorder and bipolar disorder.

@article{MarnMndez2012DifferentialEO,
  title={Differential expression of prostaglandin D2 synthase (PTGDS) in patients with attention deficit-hyperactivity disorder and bipolar disorder.},
  author={Juan Jes{\'u}s Mar{\'i}n-M{\'e}ndez and Ana Pati{\~n}o-Garc{\'i}a and Victor Segura and Felipe Ortu{\~n}o and Ma Dolores Cano-Caballero G{\'a}lvez and C{\'e}sar A. Soutullo},
  journal={Journal of affective disorders},
  year={2012},
  volume={138 3},
  pages={479-84}
}
BACKGROUND As marker genes for bipolar disorder (BP) and attention deficit hyperactivity disorder (ADHD) are not fully identified, we carried out a complete genome analysis to search for genes differentially expressed in ADHD and BP. MATERIALS AND METHODS We recruited 39 patients (30 ADHD, 9 BP), aged 7 to 23 years. For evaluation of the psychiatric diagnosis, we used a semi-structured interview based on the K-SADS-PL (DSM-IV). RNA was extracted from peripheral blood and analyzed with the… CONTINUE READING