Differential expression of microRNAs in GH-secreting pituitary adenomas

  title={Differential expression of microRNAs in GH-secreting pituitary adenomas},
  author={Zhi-gang Mao and Dongsheng He and J Zhou and B. G. Yao and Wei-Wei Xiao and Chun-Hua Chen and Yong-Hong Zhu and Hai-Jun Wang},
  booktitle={Diagnostic pathology},
BACKGROUND The purpose of this study was to (1) identify specific miRNAs in growth hormones (GH)-secreting pituitary adenomas; (2) determine the relationship between the expression of these miRNAs and tumor size, somatostatin analogs treatment, and responsiveness to somatostatin analogs (SSA). METHODS Fifteen GH-secreting adenomas patients were treated with lanreotide for 4 months before surgery. Patients with 50% reduction of GH secretion by lanreotide were considered as SSA responders… CONTINUE READING
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