Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids

Abstract

Given the emerging roles of microRNAs (miRNAs) as key regulator of mRNA stability we assessed their expression profile in paired myometrium and leiomyoma, their isolated smooth muscle cells (MSMC and LSMC), a spontaneously transformed leiomyoma smooth muscle cells (T-LSMC) and SK-LMS-1, a leiomyosarcoma cell line using microarray and real time PCR. Based on… (More)
DOI: 10.1111/j.1582-4934.2007.00207.x

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