Differential expression of microRNAs in preneoplastic gastric mucosa

  title={Differential expression of microRNAs in preneoplastic gastric mucosa},
  author={Alexander Link and Wiebke Schirrmeister and Cosima Langner and Mariya Varbanova and Jan Bornschein and Thomas Wex and P Malfertheiner},
  booktitle={Scientific reports},
Gastric carcinogenesis is a multifactorial H.pylori-triggered dynamic process that goes through a cascade of preneoplastic conditions. The expression of miRNAs in the stomach with regard to preneoplastic precursor conditions and H.pylori infection has not been investigated systematically. In this prospective proof-of-principle study, we evaluated the miRNA expression in gastric antrum and corpus mucosa from patients with chronic non-atrophic gastritis (CNAG), atrophic gastritis (AG), and GC… CONTINUE READING
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