Differential expression of matrix metalloproteinases in viral and non-viral chronic liver diseases.

@article{Ljumovic2004DifferentialEO,
  title={Differential expression of matrix metalloproteinases in viral and non-viral chronic liver diseases.},
  author={Dusanka Ljumovic and I. K. Diamantis and Athanasios K. Alegakis and Elias Kouroumalis},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2004},
  volume={349 1-2},
  pages={203-11}
}
BACKGROUND Fibrosis is a common consequence of chronic liver diseases irrespective of aetiology. Metalloproteinases play an important role in the fibrotic process participating in the balance between collagen synthesis and degradation. We examined whether matrix gelatinases and stromelysins are similarly involved in the development of viral (HCV, HBV) and non-viral (NASH) liver diseases. METHODS Hepatic mRNA levels of matrix metalloproteinase MMP-2, MMP-9, MMP-10 and MMP-11 isolated from… CONTINUE READING
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