Differential expression of matrix metalloproteinases and interleukin-8 during regeneration of human airway epithelium in vivo.

@article{Coraux2005DifferentialEO,
  title={Differential expression of matrix metalloproteinases and interleukin-8 during regeneration of human airway epithelium in vivo.},
  author={Christelle Coraux and Corinne Martinella-Catusse and B{\'e}atrice Nawrocki-Raby and Rodolphe Hajj and Henriette Burlet and Sandie Escotte and V{\'e}ronique Laplace and Philippe Birembaut and Edith Puchelle},
  journal={The Journal of pathology},
  year={2005},
  volume={206 2},
  pages={
          160-9
        }
}
In many airway diseases, the airway epithelium is severely damaged and has to regenerate rapidly to restore its function. The regeneration process involves chronological steps of epithelial cell migration, proliferation, stratification, and differentiation. The present study has used an in vivo humanized airway xenograft model in nude mice that mimics the regeneration dynamics of human airway epithelium after severe injury, and human-specific molecular tools, to study the expression profiles of… CONTINUE READING
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