Differential expression of mRNAs for neuropeptide Y-related peptides in rat nervous tissues: possible evolutionary conservation.

@article{Pieribone1992DifferentialEO,
  title={Differential expression of mRNAs for neuropeptide Y-related peptides in rat nervous tissues: possible evolutionary conservation.},
  author={Vincent A. Pieribone and Lennart Brodin and Kristina Friberg and Jonas Dahlstrand and C S{\"o}derberg and Dan Larhammar and Tomas G M H{\"o}kfelt},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1992},
  volume={12 9},
  pages={3361-71}
}
Neuropeptide Y (NPY) is the only member of its peptide family that has been isolated from the mammalian CNS. We have recently found that two different NPY-related molecules are present in the CNS of a cyclostome, the river lamprey (Lampetra fluviatilis) (Söderberg et al., 1991). Here we show that this is also true for the rat CNS, by demonstrating expression of peptide YY (PYY) mRNA in brainstem neurons distinct from those neurons that express NPY mRNA. Dissimilar oligonucleotide DNA probes… CONTINUE READING