Differential expression of human gonadotropin-releasing hormone receptor gene in pituitary and ovarian cells.

@article{Kang2000DifferentialEO,
  title={Differential expression of human gonadotropin-releasing hormone receptor gene in pituitary and ovarian cells.},
  author={Sung keun Kang and Kwai Wa Cheng and Elly Sau-wai Ngan and Billy Kwok-Chong Chow and Keith K C Choi and Peter C. K. Leung},
  journal={Molecular and cellular endocrinology},
  year={2000},
  volume={162 1-2},
  pages={157-66}
}
In terms of regulation of gene expression, gonadotropin-releasing hormone receptor (GnRHR) found in extrapituitary tissues has been suggested to be different from that in the pituitary. In the present study, we examined the molecular basis of this difference using the pituitary alphaT3-1 and ovarian carcinoma OVCAR-3 cells. As a first step, the different expression levels of GnRHR mRNA in the pituitary and ovarian cells were investigated using semi-quantitative RT-PCR. Quantitative analysis… CONTINUE READING

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