Differential expression of heat shock protein 27 in normal oral mucosa, oral epithelial dysplasia and squamous cell carcinoma.

@article{Leonardi2002DifferentialEO,
  title={Differential expression of heat shock protein 27 in normal oral mucosa, oral epithelial dysplasia and squamous cell carcinoma.},
  author={Rosy Leonardi and Giuseppe Pannone and Gaetano Magro and Yasusei Kudo and Takashi Takata and Lorenzo Lo Muzio},
  journal={Oncology reports},
  year={2002},
  volume={9 2},
  pages={261-6}
}
The aim of this study was to evaluate HSP27 expression in fetal, normal and inflamed oral mucosal epithelium and in oral premalignant epithelial lesions and in their ensuing invasive cancers. In developing human oral epithelia, immunoreactions for HSP27 were moderately observed in suprabasal keratinocytes of palate and tongue. Normal oral epithelium had an intense suprabasal positivity. In inflamed oral mucosa, HSP27 staining was stronger in basal and suprabasal keratinocytes than in normal… CONTINUE READING
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