Differential expression of cyclophilin isoforms during keratinocyte differentiation.

Abstract

Cyclophilin A, the major intracellular binding protein for the immunosuppressive drug cyclosporin A (CsA), was studied in human keratinocytes during differentiation both in vivo and in vitro. Analysis of cyclophilin by gel-filtration radiobinding-assay with tritiated CsA showed one specific radioactive peak at 17 kDa. By this technique, the levels of… (More)

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@article{ChatellardGruaz1994DifferentialEO, title={Differential expression of cyclophilin isoforms during keratinocyte differentiation.}, author={D Chatellard-Gruaz and J. H. Saurat and Giordano M. Siegenthaler}, journal={The Biochemical journal}, year={1994}, volume={303 ( Pt 3)}, pages={863-7} }