Differential expression of connexin26 and connexin32 in the pre-Bötzinger complex of neonatal and adult rat.

  title={Differential expression of connexin26 and connexin32 in the pre-B{\"o}tzinger complex of neonatal and adult rat.},
  author={Irene C. Solomon and Tomasz Halat and Raafat El-Maghrabi and Marvin H O'Neal},
  journal={The Journal of comparative neurology},
  volume={440 1},
The pre-Bötzinger complex (pre-BötC) is hypothesized to be the site for respiratory rhythm generation in mammals. Studies examining the cellular mechanisms mediating rhythm generation have focused on the role of chemically mediated synaptic interactions; however, electrotonic synaptic interactions (i.e., electrotonic coupling), which occur by means of gap junctions, may also play a role. Here, we used immunoblot and immunohistochemical analyses to determine whether the pre-BötC contains the gap… CONTINUE READING

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