Differential expression of collagen types XVIII/endostatin and XV in normal, keratoconus, and scarred human corneas.

@article{Mtt2006DifferentialEO,
  title={Differential expression of collagen types XVIII/endostatin and XV in normal, keratoconus, and scarred human corneas.},
  author={Marko M{\"a}{\"a}tt{\"a} and Ritva Heljasvaara and Raija T. Sormunen and Taina Pihlajaniemi and Helena I Autio-Harmainen and Timo M.T. Tervo},
  journal={Cornea},
  year={2006},
  volume={25 3},
  pages={341-9}
}
PURPOSE This study was designed to clarify the expression of 2 closely related collagen (Col) types XVIII and XV, and the proteolytically derived endostatin fragment of ColXVIII in normal, keratoconus, and scarred human corneas. METHODS Immunohistochemistry, in situ hybridization, immunoelectron microscopy, and Western immunoblotting were used for human corneal samples obtained from penetrating keratoplasty. RESULTS In the normal cornea, ColXVIII was immunolocalized to the corneal and… CONTINUE READING