Differential expression of anterior gradient gene AGR2 in prostate cancer

  title={Differential expression of anterior gradient gene AGR2 in prostate cancer},
  author={Erin L. Maresh and Vei Mah and Mohammad Zia Alavi and Steve Horvath and Lora Bagryanova and Emily S. Liebeskind and Laura A Knutzen and Yong Zhou and David Chia and Alvin Y. Liu and Lee A. Goodglick},
  booktitle={BMC Cancer},
The protein AGR2 is a putative member of the protein disulfide isomerase family and was first identified as a homolog of the Xenopus laevis gene XAG-2. AGR2 has been implicated in a number of human cancers. In particular, AGR2 has previously been found to be one of several genes that encode secreted proteins showing increased expression in prostate cancer cells compared to normal prostatic epithelium. Gene expression levels of AGR2 were examined in prostate cancer cells by microarray analysis… CONTINUE READING


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