Differential expression of VIP/PACAP receptor genes in breast, intestinal, and pancreatic cell lines.

@article{Waschek1995DifferentialEO,
  title={Differential expression of VIP/PACAP receptor genes in breast, intestinal, and pancreatic cell lines.},
  author={James A. Waschek and Mark L. Richards and Dawn Therese Bravo},
  journal={Cancer letters},
  year={1995},
  volume={92 2},
  pages={143-9}
}
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) are structurally-related neuropeptides that function as trophic factors in addition to their more classical roles as neurotransmitters. Binding and molecular cloning studies have shown that their actions are mediated by receptors encoded by at least three different genes. VIP binding has been demonstrated on many tumor types, and radiolabeled VIP has recently been used as a novel method to localize… CONTINUE READING

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