Differential expression of Toll-like receptors 2 and 4 in tissues of the human female reproductive tract.

@article{Pioli2004DifferentialEO,
  title={Differential expression of Toll-like receptors 2 and 4 in tissues of the human female reproductive tract.},
  author={Patricia A. Pioli and Eyal Amiel and Todd M. Schaefer and John Edward Connolly and Charles R Wira and Paul M. Guyre},
  journal={Infection and immunity},
  year={2004},
  volume={72 10},
  pages={
          5799-806
        }
}
Toll-like receptor (TLR) signal transduction is a central component of the innate immune response to pathogenic challenge. Although recent studies have begun to elucidate differences in acquired immunity in tissues of the human female reproductive tract, there is a relative paucity of work regarding innate defense mechanisms. We investigated TLR mRNA and protein expression in tissues of the human female reproductive tract. Constitutive mRNA expression of TLRs 1 to 6 was observed in fallopian… CONTINUE READING

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