Differential expression of S1 and elongation factor-1 alpha during rat development.

@article{Lee1993DifferentialEO,
  title={Differential expression of S1 and elongation factor-1 alpha during rat development.},
  author={S Lee and Lawrence Wolfraim and Erming Wang},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 32},
  pages={24453-9}
}
Elongation factor-1 alpha (EF-1 alpha) is a highly conserved protein functioning in peptide elongation during translation. A cDNA, S1, was isolated; its deduced amino acid sequence shares high similarity with mammalian EF-1 alpha s (92%). While EF-1 alpha is present in all tissues, S1 mRNA can only be detected in brain, heart, and muscle. We report here that the retropseudogene phenomenon is attributable to EF-1 alpha and not S1, the latter being represented by a single copy in the rat genome… CONTINUE READING
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