Differential expression of Rab27A/B correlates with clinical outcome in hepatocellular carcinoma.

@article{Dong2012DifferentialEO,
  title={Differential expression of Rab27A/B correlates with clinical outcome in hepatocellular carcinoma.},
  author={Wei-wei Dong and Quan Mou and Jianchu Chen and Jian-tao Cui and Wen-mei Li and Wenhua Xiao},
  journal={World journal of gastroenterology},
  year={2012},
  volume={18 15},
  pages={1806-13}
}
AIM To investigate the association of Rab27A and Rab27B expression with clinicopathological characteristics and prognosis of hepatocellular carcinoma (HCC). METHODS We used reverse transcription polymerase chain reaction (RT-PCR), real-time PCR, and Western blotting to detect Rab27A and Rab27B mRNA and protein expression in 5 human HCC lines and the immortalized hepatic HL-7702 cell line. We further examined 148 primary HCC samples matched with adjacent normal tissue and 80 non-HCC specimens… CONTINUE READING