Differential expression of Pax6 and Ngn2 between pair-generated cortical neurons.

@article{Kawaguchi2004DifferentialEO,
  title={Differential expression of Pax6 and Ngn2 between pair-generated cortical neurons.},
  author={Ayano Kawaguchi and Masaharu Ogawa and Kanako Saito and Fumio Matsuzaki and Hideyuki Okano and Takaki Miyata},
  journal={Journal of neuroscience research},
  year={2004},
  volume={78 6},
  pages={784-95}
}
Progenitor cells that generate neuron pairs ("pair progenitor cells") are implicated in mammalian cortical development, and their division has been thought to be "symmetric." However, asymmetric growth of two sister neurons generated by the division of a pair progenitor cell would lead to more efficient generation of neuronal diversity in the cortex. To explore mechanisms by which pair progenitor cells provide neuronal diversity, we examined molecular differences between a pair of neurons… CONTINUE READING