Differential expression of PCA3 and its overlapping PRUNE2 transcript in prostate cancer.

@article{Salagierski2010DifferentialEO,
  title={Differential expression of PCA3 and its overlapping PRUNE2 transcript in prostate cancer.},
  author={Maciej Salagierski and Gerald W Verhaegh and Sander A. Jannink and Frank Luiz Prado Smit and D. Scott Hessels and Jack Antonius Schalken},
  journal={The Prostate},
  year={2010},
  volume={70 1},
  pages={
          70-8
        }
}
BACKGROUND PCA3 is one of the most prostate cancer (PrCa)-specific markers described so far. Recently, a new genomic structure of PCA3 as well as new flanking and overlapping gene transcripts has been identified. Furthermore, a co-regulation of PCA3 and its overlapping gene PRUNE2(BMCC1) has been suggested. Our aim was to assess the diagnostic performance of a new PCA3 isoform (PCA3-TS4) and to study the interactions between PCA3 and BMCC1 in PrCa. METHODS We used SYBR Green quantitative (q… CONTINUE READING
BETA

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