Differential expression of MUC2 and MUC5AC mucin genes in primary ovarian and metastatic colonic carcinoma.

@article{Albarracin2000DifferentialEO,
  title={Differential expression of MUC2 and MUC5AC mucin genes in primary ovarian and metastatic colonic carcinoma.},
  author={Constance T. Albarracin and J Jafri and Anthony G. Montag and John P Hart and Shih Fan Kuan},
  journal={Human pathology},
  year={2000},
  volume={31 6},
  pages={672-7}
}
Colonic adenocarcinoma, the most common tumor metastatic to the ovary, may closely mimic primary ovarian adenocarcinoma, especially that of mucinous or endometrioid histology. The differential diagnosis is important for therapeutic considerations. Mucin gene expression is relatively organ-specific and may therefore have use in distinguishing between colonic carcinomas metastatic to the ovary and primary ovarian tumors. In this study, we compared the expression of MUC2 and MUC5AC apomucins in 10… CONTINUE READING