Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis


M3 muscarinic receptor (M3R) activation promotes colon cancer cell proliferation, migration, and invasion in vitro. Although over-expression of CHRM3, the gene encoding M3R, is reported in primary colon cancers, expression of M3R itself has not been studied in colon neoplasia. We compared M3R expression in normal colon to colon adenomas, and primary and… (More)
DOI: 10.18632/oncotarget.15500


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