Differential expression of alpha-methylacyl-coenzyme A racemase in colorectal carcinoma bears clinical and pathologic significance.

@article{Lin2007DifferentialEO,
  title={Differential expression of alpha-methylacyl-coenzyme A racemase in colorectal carcinoma bears clinical and pathologic significance.},
  author={Anne G Lin and Martin Ross Weiser and David S. Klimstra and Philip B. Paty and Laura H. Tang and Hikmat A. Al-Ahmadie and Sun Hoo Park and Jos{\'e} G. Guillem and Larissa K. F. Temple and W. Douglas Wong and William L. Gerald and Jinru Shia},
  journal={Human pathology},
  year={2007},
  volume={38 6},
  pages={850-6}
}
alpha-methylacyl-coenzyme A racemase (AMACR) is a recently discovered biomarker that is shown to be overexpressed in some prostatic carcinomas and associated with prostatic cancer progression. Given that AMACR plays an important role in peroxisomal beta-oxidation of branched-chain fatty acids from red meat and dairy products, and that consumption of red meat may increase risk of developing colon cancer as suggested by epidemiological studies, it is plausible to explore the function of AMACR in… CONTINUE READING

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