Differential expression of 2′∶3′-cyclic nucleotide 3′-phosphodiesterase in cultured central, peripheral, and extraneural cells

@article{Sprinkle1985DifferentialEO,
  title={Differential expression of 2′∶3′-cyclic nucleotide 3′-phosphodiesterase in cultured central, peripheral, and extraneural cells},
  author={Terry Joe Sprinkle and F. Arthur McMorris and Jun Yoshino and George H. De Vries},
  journal={Neurochemical Research},
  year={1985},
  volume={10},
  pages={919-931}
}
The relative levels of the central nervous system myelin marker enzyme 2′:3′-cyclic nucleotide 3′-phosphodiesterase (EC 3.1.4.37, CNPase) were determined in neuroblastoma, astrocyte, oligodendrocyte and Schwann cell cultures and in freshly isolated human lymphocytes and platelets. The highest specific activities were associated with the cells that elaborate myelin membrane in the central and peripheral nervous system, oligodendrocytes and Schwann cells, respectively. Antiserum to bovine CNPase… CONTINUE READING

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