Differential expression between pilocytic and anaplastic astrocytomas: identification of apolipoprotein D as a marker for low-grade, non-infiltrating primary CNS neoplasms.

@article{Hunter2002DifferentialEB,
  title={Differential expression between pilocytic and anaplastic astrocytomas: identification of apolipoprotein D as a marker for low-grade, non-infiltrating primary CNS neoplasms.},
  author={Stephen B. Hunter and Andrew Young and Jeffrey Olson and Daniel J. Brat and Geoffrey Bowers and Josiah N. Wilcox and David L Jaye and Savvas Mendrinos and Andrew S. Neish},
  journal={Journal of neuropathology and experimental neurology},
  year={2002},
  volume={61 3},
  pages={275-81}
}
Fibrillary astrocytoma, the most common primary central nervous system neoplasm, is infiltrating, rapidly proliferating, and almost invariably fatal. This contrasts with the biologically distinct pilocytic astrocytoma, which is circumscribed, often cystic, slowly proliferating, and associated with a favorable long-term outcome. Diagnostic markers for distinguishing pilocytic astrocytomas from infiltrating anaplastic astrocytomas are currently not available. To identify genes that might either… CONTINUE READING

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