Differential expression and pathological significance of autocrine motility factor/glucose‐6‐phosphate isomerase expression in human lung carcinomas
@article{Dobashi2006DifferentialEA, title={Differential expression and pathological significance of autocrine motility factor/glucose‐6‐phosphate isomerase expression in human lung carcinomas}, author={Yoh Dobashi and Hayato Watanabe and Y Sato and Souichi Hirashima and Takashi Yanagawa and Hirochika Matsubara and Akishi Ooi}, journal={The Journal of Pathology}, year={2006}, volume={210} }
To clarify the involvement of autocrine motility factor (AMF) in the phenotype and biological profiles of human lung carcinomas, we analysed protein and mRNA expression in a total of 180 cases. Immunohistochemistry revealed positive staining in 67.2%, with the highest frequency in squamous cell carcinoma (SCC; 90.8%) and the lowest in small cell carcinoma (SmCC; 27.8%). In SCC, the staining frequency and intensity correlated with the degree of morphological differentiation. Generally, the…
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