Differential expression and function of PACAP and VIP receptors in four human colonic adenocarcinoma cell lines.

@article{Lelievre1998DifferentialEA,
  title={Differential expression and function of PACAP and VIP receptors in four human colonic adenocarcinoma cell lines.},
  author={Vincent Lelievre and Annette Meunier and Evelyne Caigneaux and Jack Falc{\'o}n and J. M. Muller},
  journal={Cellular signalling},
  year={1998},
  volume={10 1},
  pages={13-26}
}
Human colonic adenocarcinoma cell lines have conserved several features of the native tissue. Among these is the expression of cell surface receptors for hormones and neurotransmitters that may be involved in the regulation of proliferation and differentiation processes in these cancer cells. Here, we confirm that high-affinity binding sites for the Vasoactive Intestinal Polypeptide (VIP) and for the VIP analogue Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP), were expressed in 4… CONTINUE READING

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VPAC and PAC receptors: From ligands to function.

Pharmacology & therapeutics • 2009
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