Differential effects produced by ketamine on oscillatory activity recorded in the rat hippocampus, dorsal striatum and nucleus accumbens.

@article{Hunt2011DifferentialEP,
  title={Differential effects produced by ketamine on oscillatory activity recorded in the rat hippocampus, dorsal striatum and nucleus accumbens.},
  author={M. J. Hunt and Monika Falinska and Szymon Łęski and Daniel K. W{\'o}jcik and Stefan Kasicki},
  journal={Journal of psychopharmacology},
  year={2011},
  volume={25 6},
  pages={808-21}
}
Previously, we showed that NMDA antagonists enhance high-frequency oscillations (130-180 Hz) in the nucleus accumbens. However, whether NMDA antagonists can enhance high-frequency oscillations in other brain regions remains unclear. Here, we used monopolar, bipolar and inverse current source density techniques to examine oscillatory activity in the hippocampus, a region known to generate spontaneous ripples (∼200 Hz), its surrounding tissue, and the dorsal striatum, neuroanatomically related to… CONTINUE READING

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