Differential effects of two citrus flavanones on bone quality in senescent male rats in relation to their bioavailability and metabolism.

@article{Habauzit2011DifferentialEO,
  title={Differential effects of two citrus flavanones on bone quality in senescent male rats in relation to their bioavailability and metabolism.},
  author={V. Habauzit and S. Sacco and {\'A}. Gil-Izquierdo and A. Trzeciakiewicz and C. Morand and D. Barron and S. Pinaud and E. Offord and M. Horcajada},
  journal={Bone},
  year={2011},
  volume={49 5},
  pages={
          1108-16
        }
}
The effect of hesperidin (Hp) and naringin (Nar), two major citrus flavanones, on the regulation of bone metabolism was examined in male senescent rats. Twenty -month -old gonad-intact male Wistar rats received a casein-based diet supplemented with or without either 0.5% hesperidin (Hp), 0.5% naringin (Nar) or a mix of both flavanones (Hp+Nar, 0.25% each). After 3 months, daily Hp intake significantly improved femoral bone integrity as reflected by improvements in total and regional bone… Expand
Effect of Hesperidin With and Without a Calcium (Calcilock) Supplement on Bone Health in Postmenopausal Women.
Nutritional Programming of Bone Structure in Male Offspring by Maternal Consumption of Citrus Flavanones
Re-appraising the potential of naringin for natural, novel orthopedic biotherapies
Physical activity increases the bioavailability of flavanones after dietary aronia-citrus juice intake in triathletes.
Hesperidin Prevents Androgen Deficiency‐induced Bone Loss in Male Mice
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 57 REFERENCES
Hesperidin inhibits ovariectomized-induced osteopenia and shows differential effects on bone mass and strength in young and adult intact rats.
Citrus juice modulates bone strength in male senescent rat model of osteoporosis.
Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice.
Feeding orange pulp improved bone quality in a rat model of male osteoporosis.
Various selected vegetables, fruits, mushrooms and red wine residue inhibit bone resorption in rats.
Flavanone metabolism in healthy and tumor-bearing rats.
Molecular mechanism of hesperetin-7-O-glucuronide, the main circulating metabolite of hesperidin, involved in osteoblast differentiation.
Hesperetin stimulates differentiation of primary rat osteoblasts involving the BMP signalling pathway.
...
1
2
3
4
5
...