Differential effects of three canonical Toxoplasma strains on gene expression in human neuroepithelial cells.

@article{Xiao2011DifferentialEO,
  title={Differential effects of three canonical Toxoplasma strains on gene expression in human neuroepithelial cells.},
  author={Jianchun Xiao and Lorraine Jones-Brando and C Conover Talbot and Robert Yolken},
  journal={Infection and immunity},
  year={2011},
  volume={79 3},
  pages={1363-73}
}
Strain type is one of the key factors suspected to play a role in determining the outcome of Toxoplasma infection. In this study, we examined the transcriptional profile of human neuroepithelioma cells in response to representative strains of Toxoplasma by using microarray analysis to characterize the strain-specific host cell response. The study of neural cells is of interest in light of the ability of Toxoplasma to infect the brain and to establish persistent infection within the central… CONTINUE READING

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