Differential effects of six structurally related benzodiazepines on some ethological measures of timidity, aggression and locomotion in mice

@article{Krsiak1990DifferentialEO,
  title={Differential effects of six structurally related benzodiazepines on some ethological measures of timidity, aggression and locomotion in mice},
  author={Miloslav Krsiak and A. {\vS}ulcov{\'a}},
  journal={Psychopharmacology},
  year={1990},
  volume={101},
  pages={396-402}
}
The effects were compared of three 2' chloro-phenyl-benzodiazepines (triazolam, clonazepam and lorazepam) and three corresponding 2' deschloro-phenylderivatives (alprazolam, nitrazepam and oxazepam, respectively) on the incidence of six ethological elements in both timid and aggressive singly-housed male mice, treated with drugs in paired interactions with untreated non-aggressive males. Alprazolam and oxazepam reduced defensive upright postures and escapes at doses which did not reduce rearing… CONTINUE READING
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