Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes.

@article{Tavares2005DifferentialEO,
  title={Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes.},
  author={J. Tavares and A. Ouaissi and P. Lin and A. Tom{\'a}s and A. Cordeiro-da-Silva},
  journal={International journal for parasitology},
  year={2005},
  volume={35 6},
  pages={
          637-46
        }
}
The natural polyamines are ubiquitous polycationic compounds that play important biological functions in cell growth and differentiation. In the case of protozoan species that are causative agents of important human diseases such as Leishmaniasis, an exogenous supply of polyamines supports parasite proliferation. In the present study, we have investigated the effect of three polyamine derivatives, (namely bis-naphthalimidopropyl putrescine (BNIPPut), spermidine (BNIPSpd) and spermine (BNIPSpm… Expand
In vitro leishmanicidal activity of N-dodecyl-1,2-ethanediamine.
Polyamine-based analogs and conjugates as antikinetoplastid agents.
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