Differential effects of paradoxical sleep deprivation on memory and oxidative stress

  title={Differential effects of paradoxical sleep deprivation on memory and oxidative stress},
  author={Alisson Menezes Ara{\'u}jo Lima and Veralice Meireles Sales de Bruin and Emiliano Ricardo Vasconcelos Rios and Pedro Felipe Carvalhedo de Bruin},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
Sleep has important functions for every organ in the body and sleep deprivation (SD) leads to disorders that cause irreparable damage. The aim of this study was to investigate behavioral and brain structural alterations in mice deprived of paradoxical sleep for 48 and 72 h. Working memory, aversive memory as well as levels of nitric oxide (NO) and thiobarbituric acid reactive substances (TBARS) in the hippocampus, body striatum, and prefrontal cortex were evaluated. Working memory was affected… CONTINUE READING
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The effects of long - term sleep deprivation on the long - term potentiation in the dentate gyrus and brain oxidation status in rats

GR Thatcher, BM Bennett, JN Reynolds
Neurosci Res • 2006
View 1 Excerpt
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A role for cortical nNOS/NK1 neurons in coupling homeostatic sleep drive to EEG slow wave activity.

Proceedings of the National Academy of Sciences of the United States of America • 2013
View 1 Excerpt

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