Differential effects of paradoxical sleep deprivation on memory and oxidative stress

@article{Lima2013DifferentialEO,
  title={Differential effects of paradoxical sleep deprivation on memory and oxidative stress},
  author={Alisson Menezes Ara{\'u}jo Lima and Veralice Meireles Sales de Bruin and Emiliano Ricardo Vasconcelos Rios and Pedro Felipe Carvalhedo de Bruin},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2013},
  volume={387},
  pages={399-406}
}
Sleep has important functions for every organ in the body and sleep deprivation (SD) leads to disorders that cause irreparable damage. The aim of this study was to investigate behavioral and brain structural alterations in mice deprived of paradoxical sleep for 48 and 72 h. Working memory, aversive memory as well as levels of nitric oxide (NO) and thiobarbituric acid reactive substances (TBARS) in the hippocampus, body striatum, and prefrontal cortex were evaluated. Working memory was affected… CONTINUE READING
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