Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens

@inproceedings{Tukey2013DifferentialEO,
  title={Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens},
  author={David S. Tukey and Michelle K. Lee and Duo Xu and Sarah E. Eberle and Yossef Goffer and Toby R Manders and Edward B Ziff and Jing Tian Wang},
  booktitle={Molecular Brain},
  year={2013}
}
Pain and natural rewards such as food elicit different behavioral effects. Both pain and rewards, however, have been shown to alter synaptic activities in the nucleus accumbens (NAc), a key component of the brain reward system. Mechanisms by which external stimuli regulate plasticity at NAc synapses are largely unexplored. Medium spiny neurons (MSNs) from the NAc receive excitatory glutamatergic inputs and modulatory dopaminergic and cholinergic inputs from a variety of cortical and subcortical… CONTINUE READING
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