Differential effects of isotonic and hypotonic 4% albumin solution on intracranial pressure and renal perfusion and function.

OBJECTIVES Albumin is used to resuscitate trauma patients but may increase intracranial pressure (ICP). Its effects on renal blood flow and function are unknown. Our aim was to examine the effects of hypertonic albumin on ICP and renal function, and if any effects are due to the hypotonicity of the solution containing albumin or to albumin itself. DESIGN… CONTINUE READING