Differential effects of hydrogen peroxide on indices of endothelial cell function

@article{Ager1984DifferentialEO,
  title={Differential effects of hydrogen peroxide on indices of endothelial cell function},
  author={Ann Ager and John L. Gordon},
  journal={The Journal of Experimental Medicine},
  year={1984},
  volume={159},
  pages={592 - 603}
}
The responses of pig aortic endothelial cells to sublethal doses of potentially toxic stimuli were investigated by monitoring K+ efflux, prostaglandin production, and the release of cytoplasmic purines. Xanthine plus xanthine oxidase reversibly stimulated these three parameters of endothelial cell function at doses that were not cytotoxic, as measured by chromium release, adenine uptake, and vital dye exclusion. The effects of xanthine plus xanthine oxidase were inhibited by catalase but not by… CONTINUE READING

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