Differential effects of haloperidol, clozapine and olanzapine on learning and memory functions in mice

@article{Hou2006DifferentialEO,
  title={Differential effects of haloperidol, clozapine and olanzapine on learning and memory functions in mice},
  author={Yue mei Hou and Chun fu Wu and J. Y. Yang and Tao Guo},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2006},
  volume={30},
  pages={1486-1495}
}
Many schizophrenic patients exhibit impairments in neurocognitive functions. Typical antipsychotic drugs such as haloperidol, have limited or even detrimental influence on cognitive functions. In contrast, atypical antipsychotic drugs, such as clozapine and olanzapine, may improve memory function in schizophrenics. However, only a few studies have been conducted to directly compare the effects of olanzapine, clozapine and haloperidol on memory functions in animal models. Thus, their effects on… CONTINUE READING
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