Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine.

@article{Yu2001DifferentialEO,
  title={Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine.},
  author={Chun Hong Yu and Yu Mi Lee and Yeo Pyo Yun and Hun Sung Yoo},
  journal={Archives of pharmacal research},
  year={2001},
  volume={24 2},
  pages={136-43}
}
Fumonisins are specific inhibitors of ceramide synthase in sphingolipid metabolism. An alteration in sphingolipid metabolism as a result of fumonisin exposure is related to cell death (Yoo et al., 1992). The objective of this study was to investigate whether elevated free sphinganine levels are related to the sensitivity of cultured cells to fumonisin exposure. Fumonisin B1 elevated the intracellular free sphinganine concentraions in both LLC-PK1 and Chinese hamster ovary (CHO) cells. However… CONTINUE READING
9 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…