Differential effects of distinct central nervous system regions on cell migration and axonal extension of neural precursor transplants.

Abstract

Transplantation of neural precursor cells (NPCs) is a promising therapeutic strategy in CNS injury. However, the adult CNS lacks instructive signals present during development and, depending on the region and type of transplant, may be inhibitory for neuron generation and axonal growth. We examined the effects of the white matter in different regions of the… (More)
DOI: 10.1002/jnr.23099

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