Differential effects of dietary whey, casein and soya on colonic DNA damage and large bowel SCFA in rats fed diets low and high in resistant starch

@article{Toden2007DifferentialEO,
  title={Differential effects of dietary whey, casein and soya on colonic DNA damage and large bowel SCFA in rats fed diets low and high in resistant starch},
  author={Shusuke Toden and A. Bird and D. Topping and M. Conlon},
  journal={British Journal of Nutrition},
  year={2007},
  volume={97},
  pages={535 - 543}
}
  • Shusuke Toden, A. Bird, +1 author M. Conlon
  • Published 2007
  • Biology, Medicine
  • British Journal of Nutrition
    • Feeding higher levels of dietary animal protein (as casein or red meat) increases colonic DNA damage and thins the colonic mucus barrier in rats. Feeding resistant starch (RS) reverses these changes and increases large bowel SCFA. The present study examined whether high dietary dairy (casein or whey) or plant (soya) proteins had similar adverse effects and whether dietary RS was protective. Adult male rats were fed diets containing 15 or 25 % casein, whey or soya protein with or without 48… CONTINUE READING
    View on Cambridge Press
    cambridge.org
    67 Citations
    Highly Influential Citations
    3
    Background Citations
    27
    Methods Citations
    3
    Results Citations
    4
    67 Citations
    Citation Type

    Citation Type

    High red meat diets induce greater numbers of colonic DNA double-strand breaks than white meat in rats: attenuation by high-amylose maize starch.
    • 89
    • PDF
    Butyrylated starch protects colonocyte DNA against dietary protein-induced damage in rats.
    • 41
    • PDF
    Interactive and individual effects of dietary non-digestible carbohydrates and oils on DNA damage, SCFA and bacteria in the large bowel of rats
    • 15
    • PDF
    Dietary protein source and butyrylated high-amylose maize starch included in a high-protein diet determines the urinary metabolome of rats
    Interactive Effects of Indigestible Carbohydrates, Protein Type, and Protein Level on Biomarkers of Large Intestine Health in Rats
    • 17
    • Highly Influenced
    • PDF
    Effects of Dietary Beef and Chicken With and Without High Amylose Maize Starch on Blood Malondialdehyde, Interleukins, IGF-I, Insulin, Leptin, MMP-2, and TIMP-2 Concentrations in Rats
    • 28
    Increase in dietary protein content exacerbates colonic inflammation and tumorigenesis in azoxymethane-induced mouse colon carcinogenesis
    • 6
    • PDF
    Tempe Consumption Modulates Fecal Secondary Bile Acids, Mucins, Immunoglobulin A, Enzyme Activities, and Cecal Microflora and Organic Acids in Rats
    • 17
    Xylo-Oligosaccharides and Inulin Affect Genotoxicity and Bacterial Populations Differently in a Human Colonic Simulator Challenged with Soy Protein
    • 10
    • PDF
    Resistant starches as a vehicle for delivering health benefits to the human large bowel
    • 40

    References

    SHOWING 1-10 OF 72 REFERENCES
    Resistant starch prevents colonic DNA damage induced by high dietary cooked red meat or casein in rats
    • 100
    Dietary soybean protein compared with casein damages colonic epithelium and stimulates colonic epithelial proliferation in rats.
    • 34
    • Highly Influential
    Resistant Starch Attenuates Colonic DNA Damage Induced by Higher Dietary Protein in Rats
    • 84
    Dairy proteins protect against dimethylhydrazine-induced intestinal cancers in rats.
    • 203
    • Highly Influential
    Dietary exposure to soy or whey proteins alters colonic global gene expression profiles during rat colon tumorigenesis
    • 159
    Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides.
    • 2,234
    • PDF
    Resistant proteins alter cecal short-chain fatty acid profiles in rats fed high amylose cornstarch.
    • 123
    • PDF
    Dietary whey protein protects against azoxymethane-induced colon tumors in male rats.
    • R. Hakkak, S. Korourian, M. Ronis, J. Johnston, T. Badger
    • Biology, Medicine
    • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
    • 2001
    • 66
    • PDF
    A diet high in fat and meat but low in dietary fibre increases the genotoxic potential of 'faecal water'.
    • 93
    • PDF
    Effects of resistant starch and nonstarch polysaccharides on colonic luminal environment and genotoxin-induced apoptosis in the rat.
    • 70
    • PDF