Differential effects of cocaine and ketamine on time estimation: Implications for neurobiological models of interval timing

@article{Cheng2006DifferentialEO,
  title={Differential effects of cocaine and ketamine on time estimation: Implications for neurobiological models of interval timing},
  author={Ruey-Kuang Cheng and Christopher J. MacDonald and Warren H. Meck},
  journal={Pharmacology Biochemistry and Behavior},
  year={2006},
  volume={85},
  pages={114-122}
}
Effects of Amphetamine and Cocaine on Behavior Maintained by Differential Reinforcement of Low-Rate-Response (DRL) Schedule
TLDR
The effects of amphetamines and cocaine on DRL behavior as reviewed here further highlight the need for additional research to probe neurobehavioral mechanisms that may underlie DRLbehavior as manifested by both burst responding and timing the emission of the operant response.
Ethanol effects on impulsivity in two mouse strains: similarities to diazepam and ketamine
TLDR
Ethanol's ability to increase impulsivity in the 5-CSRTT is mediated by both common and different neurotransmitter systems in the two strains of mice and is dependent on the task's parameters.
Acute ethanol potentiates the clock-speed enhancing effects of nicotine on timing and temporal memory.
  • W. Meck
  • Medicine, Biology
    Alcoholism, clinical and experimental research
  • 2007
TLDR
The observation that ethanol pretreatment potentiates the clock-speed enhancing effects of subsequently administered nicotine is discussed in terms of the role of alpha7-nicotinic acetylcholine receptors and dopamine-glutamate interactions in cortico-striatal circuits thought to subserve interval timing.
Habit formation and the loss of control of an internal clock: inverse relationship between the level of baseline training and the clock-speed enhancing effects of methamphetamine
TLDR
A transition from DA-sensitive to DA-insensitive mechanisms is proposed to account for the loss of control of clock speed, as timing behaviors associated with the PI procedure gradually become learned habits through the strengthening of DA–glutamate connections.
Time Perception in Cocaine-Dependent Patients
TLDR
Regardless of the time interval tested, the results showed comparable temporal ability in patients and controls, but higher temporal variability in patients, consistent with impairment of frontally-mediated cognitive functions involved in time perception rather than impairment in time processing per se.
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