Differential effects of chronic ethanol administration and withdrawal on gamma-aminobutyric acid type A and NMDA receptor subunit proteins in male and female rat brain.

@article{Devaud2004DifferentialEO,
  title={Differential effects of chronic ethanol administration and withdrawal on gamma-aminobutyric acid type A and NMDA receptor subunit proteins in male and female rat brain.},
  author={Leslie L. Devaud and Paul E. Alele},
  journal={Alcoholism, clinical and experimental research},
  year={2004},
  volume={28 6},
  pages={957-65}
}
BACKGROUND Investigations have shown that chronic ethanol exposure results in selective alterations in levels of gamma-aminobutyric acid (GABA)A and NMDA receptor subunits. We previously reported significant sex differences in these chronic ethanol-induced adaptations. Because we have more recently found important sex differences in timing for the development of and recovery from ethanol dependence, we wanted to ascertain whether there were associations between overt expression of withdrawal… CONTINUE READING