Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury.

@article{Maier2009DifferentialEO,
  title={Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury.},
  author={Irin C. Maier and Ronaldo M Ichiyama and Gr{\'e}goire Courtine and Lisa J. Schnell and Igor A. Lavrov and V. Reggie Edgerton and Martin E. Schwab},
  journal={Brain : a journal of neurology},
  year={2009},
  volume={132 Pt 6},
  pages={
          1426-40
        }
}
Locomotor training on treadmills can improve recovery of stepping in spinal cord injured animals and patients. Likewise, lesioned rats treated with antibodies against the myelin associated neurite growth inhibitory protein, Nogo-A, showed increased regeneration, neuronal reorganization and behavioural improvements. A detailed kinematic analysis showed that the hindlimb kinematic patterns that developed in anti-Nogo-A antibody treated versus treadmill trained spinal cord injured rats were… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 62 CITATIONS, ESTIMATED 50% COVERAGE

FILTER CITATIONS BY YEAR

2009
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

Changes in motoneuron properties and synaptic inputs related to step training after spinal cord transection in rats.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2007
VIEW 5 EXCERPTS

Step training reinforces specific spinal locomotor circuitry in adult spinal rats.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2008
VIEW 2 EXCERPTS