Differential effects of amphetamine isomers on dopamine release in the rat striatum and nucleus accumbens core
@article{Glaser2004DifferentialEO, title={Differential effects of amphetamine isomers on dopamine release in the rat striatum and nucleus accumbens core}, author={Paul E. A. Glaser and Theresa C. Thomas and B. Matthew Joyce and Francisco Xavier Castellanos and Greg A. Gerhardt}, journal={Psychopharmacology}, year={2004}, volume={178}, pages={250-258} }
RationaleCurrent medications for attention-deficit/hyperactivity disorder (ADHD) include some single isomer compounds [dextroamphetamine (d-amphetamine, dexedrine) and dexmethylphenidate (Focalin)] and some racemic compounds [methylphenidate and mixed-salts amphetamine (Adderall)]. Adderall, which contains approximately 25% l-amphetamine, has been successfully marketed as a first-line medication for ADHD. Although different clinical effects have been observed for d-amphetamine, Adderall, and…
27 Citations
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