Differential effects of alprazolam and buspirone upon acquisition, retention, and retrieval processes in memory.

@article{Barbee1992DifferentialEO,
  title={Differential effects of alprazolam and buspirone upon acquisition, retention, and retrieval processes in memory.},
  author={James G. Barbee and F William Black and Alexandre A. Todorov},
  journal={The Journal of neuropsychiatry and clinical neurosciences},
  year={1992},
  volume={4 3},
  pages={308-14}
}
A group of 125 healthy young adults was given a memory battery 1 hour after administration of alprazolam (0.5 and 1.0 mg), buspirone (5 and 10 mg), and placebo under single-dose, double-blind conditions. On the wordlist recall battery and a 24-hour retest, alprazolam appeared to impair acquisition and retention in dosages of 1.0 mg; buspirone did not adversely affect test performance at either dosage. On the basis of a 3-stage model of memory, a neuroantomical/neurophysiological model is… CONTINUE READING