Differential effects of acute hypertriglyceridemia on insulin action and insulin receptor autophosphorylation.

Abstract

Experimentally induced hypertriglyceridemia (HTG) and high plasma free fatty acid (FFA) levels impair in vivo insulin action. To determine if this is a consequence of impaired in vivo insulin receptor autophosphorylation and related to defective receptor signaling, hyperinsulinemic euglycemic clamps, indirect calorimetry, and skeletal muscle biopsies were… (More)

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Cite this paper

@article{Gumbiner1996DifferentialEO, title={Differential effects of acute hypertriglyceridemia on insulin action and insulin receptor autophosphorylation.}, author={Barry Gumbiner and Janusz Mucha and Jennifer Lindstrom and Ishpal Rekhi and J. N. Livingston}, journal={The American journal of physiology}, year={1996}, volume={270 3 Pt 1}, pages={E424-9} }